Positive Phase 3 INTerpath-001 results for Moderna and Merck’s personalized mRNA neoantigen therapy intismeran autogene (mRNA-4157/V940) plus Keytruda in resected high-risk melanoma, announced August 19, 2026, represent the key catalyst. The trial met recurrence-free and distant metastasis-free survival endpoints, marking the first late-stage success for this individualized mRNA approach and triggering immediate plans to share data with regulators for potential filing. With prior breakthrough therapy designation, sustained Phase 2 durability signals, and active regulatory engagement underway, traders see strong momentum toward a Biologics License Application submission well before the June 2027 deadline despite typical review timelines.
Экспериментальная сводка, созданная ИИ на основе данных Polymarket. Это не является торговой рекомендацией и не влияет на то, как разрешается этот рынок. · ОбновленоВакцина против рака кожи BLA подана до 30 июня 2027 года?
Да
$30,124 Объем
$30,124 Объем
Да
$30,124 Объем
$30,124 Объем
Intismeran autogene refers to the individualized neoantigen therapy developed by Moderna and Merck and evaluated in the Phase 3 INTerpath-001 trial (NCT05933577), also known as mRNA-4157 and V940, together with any brand, trade, or nonproprietary name later assigned to that product, as well as any renamed or modified version that the relevant company or the FDA identify as the same product or a direct continuation of the V940/mRNA-4157 program.
A qualifying application must seek FDA licensure of intismeran autogene through a Biologics License Application (BLA). An original BLA or a resubmission of such a BLA following FDA action will qualify. The application may cover any indication.
A qualifying announcement must come from the relevant company submitting the BLA, the FDA, or authorized representatives thereof.
The submission must already have occurred at the time of the statement. A statement of intent, plan, guidance, or expected timing will not qualify.
If the FDA grants approval of intismeran autogene on or before June 30, 2027, 11:59 PM ET, this market will resolve to "Yes", whether or not a submission was separately disclosed.
The primary resolution source for this market will be official communications from the company submitting the BLA, the FDA, or authorized representatives thereof; however, a consensus of credible reporting may also be used.
Открытие рынка: Aug 19, 2026, 2:46 PM ET
Resolver
0x65070BE91...Intismeran autogene refers to the individualized neoantigen therapy developed by Moderna and Merck and evaluated in the Phase 3 INTerpath-001 trial (NCT05933577), also known as mRNA-4157 and V940, together with any brand, trade, or nonproprietary name later assigned to that product, as well as any renamed or modified version that the relevant company or the FDA identify as the same product or a direct continuation of the V940/mRNA-4157 program.
A qualifying application must seek FDA licensure of intismeran autogene through a Biologics License Application (BLA). An original BLA or a resubmission of such a BLA following FDA action will qualify. The application may cover any indication.
A qualifying announcement must come from the relevant company submitting the BLA, the FDA, or authorized representatives thereof.
The submission must already have occurred at the time of the statement. A statement of intent, plan, guidance, or expected timing will not qualify.
If the FDA grants approval of intismeran autogene on or before June 30, 2027, 11:59 PM ET, this market will resolve to "Yes", whether or not a submission was separately disclosed.
The primary resolution source for this market will be official communications from the company submitting the BLA, the FDA, or authorized representatives thereof; however, a consensus of credible reporting may also be used.
Resolver
0x65070BE91...Positive Phase 3 INTerpath-001 results for Moderna and Merck’s personalized mRNA neoantigen therapy intismeran autogene (mRNA-4157/V940) plus Keytruda in resected high-risk melanoma, announced August 19, 2026, represent the key catalyst. The trial met recurrence-free and distant metastasis-free survival endpoints, marking the first late-stage success for this individualized mRNA approach and triggering immediate plans to share data with regulators for potential filing. With prior breakthrough therapy designation, sustained Phase 2 durability signals, and active regulatory engagement underway, traders see strong momentum toward a Biologics License Application submission well before the June 2027 deadline despite typical review timelines.
Экспериментальная сводка, созданная ИИ на основе данных Polymarket. Это не является торговой рекомендацией и не влияет на то, как разрешается этот рынок. · Обновлено


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