The crushing Republican losses in the November 2026 midterms have accelerated cabinet and White House turnover in the second Trump administration, with multiple senior officials departing in the immediate aftermath. Susie Wiles stepped down as chief of staff and was replaced by Stephen Miller, while recent exits include several department heads and DOJ officials such as Harmeet Dhillon, Brett Shumate, and John Eisenberg. Trump has publicly signaled plans for additional limited changes, consistent with already elevated rates of political appointee departures—nearly half serving under one year. These developments, alongside lingering policy frictions and post-election oversight pressures, shape trader assessments of further exits before 2027. Upcoming congressional sessions and any new nominations could influence the pace of additional shifts.