Recent Republican midterm losses, which handed Democrats control of Congress and raised prospects of aggressive oversight, have accelerated departures from the second Trump administration. White House Chief of Staff Susie Wiles was replaced by Stephen Miller days after the election, joining a string of high-profile exits this year that include Attorney General Pam Bondi, Homeland Security Secretary Kristi Noem, Labor Secretary Lori Chavez-DeRemer, Director of National Intelligence Tulsi Gabbard, and multiple press secretaries. Additional Justice Department officials have resigned amid fears of investigations, while Trump has signaled further Cabinet adjustments. These developments, alongside historical patterns of second-term turnover and pressure on remaining officials, shape trader assessments of who may exit before the end of 2026.