A large multistate cyclosporiasis outbreak has driven U.S. case counts far above historical baselines, with CDC reporting 13,895 laboratory-confirmed domestically acquired cases since May 1, 2026—versus just 1,180 for the comparable May–August 31 period in 2025—plus over 10,000 additional cases under investigation across at least 34 states. The surge stems primarily from contaminated fresh produce, including iceberg lettuce traced to Mexican processors, with transmission occurring via the fecal-oral route after the Cyclospora cayetanensis oocysts sporulate in the environment. CDC surveillance notes that underdiagnosis and underreporting likely mean true incidence is higher, and seasonal patterns show continued rises through late summer. Weekly case updates and any new traceback findings from FDA or state health departments through August 31 represent the key data points that could shift final totals relative to prior years.