Recent detections of New World screwworm (Cochliomyia hominivorax) in the U.S. began with a confirmed case on June 3, 2026, in a calf from Zavala County, Texas, marking the first domestic livestock infestation since 1966. USDA-APHIS reports have since identified additional livestock cases (calves and a goat) in La Salle, Zavala, and Gillespie counties through June 8–9, all within Texas, alongside one case in a dog in Lea County, New Mexico. No confirmed livestock infestations have occurred outside Texas as of the latest official updates. The parasite’s northward advance from Central America and Mexico since 2023, driven by wound-infesting larvae that can rapidly multiply in livestock and wildlife, has prompted expanded USDA surveillance, sterile insect releases, quarantines, and border monitoring. Resolution hinges on laboratory confirmation of larvae in livestock wounds via USDA channels, with new case reports or model updates from APHIS and state animal health officials likely to shift implied probabilities. Historical eradication success relied on the sterile insect technique, but current conditions near the border elevate risks of further spread before containment stabilizes.